![]() ![]() For us, such a feature has however become more and more desirable, precipitated by the current COVID epidemic and the constraints of home-working, which are likely also experienced by other researchers across the world. All of them are locked behind high licensing fees and may not be available to install on the individual computers of multiple researchers, or require connection to local databases, making them hardly available offsite. Other commercial solutions exist for the creation and visualization of plate data ( Pipeline Pilot, Spotfire and Dotmatics, among others). ![]() While this is ideal from an automation point-of-view our experience shows that such files are uncomfortable to read and work with for a regular lab worker, who will prefer a more visual, plate-like (or matrix-like) representation of the data, usually under the form of heatmap.Įvery plate reader or plate-friendly device will propose such a tool to prepare plate layouts and analyze their associated data. Most of the automation or plate reading software use or generate data files as lists, using the well name or row/column indices to locate the values at their relevant location. Screening activities have a heavy reliance on multi-well plates, but other common applications like enzyme-linked immunosorbent assays (ELISA) or dose-response curves are also commonly performed in multi-well plates. The greater availability of automation equipment, for example readers, washers and incubators, allows easy upscaling from a couple of plates to a full library of hundreds of plates. ![]() From 6 to 1536 wells, made with various materials (plastic, glass) and for various purposes (optical measurements, filtration, storage), they can accommodate a broad range of assays and conditions. Multi-well plates offer a convenient and compact way to test multiple conditions in one go. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. VD was supported by the French Ministry of Foreign Affairs. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The application can be accessed at the following address: The source code is available under the MIT license on the PlateEditor repository on GitHub ( ) and the latest version of the full application can be downloaded as a zip archive on SourceForge ( ).įunding: This work was supported by the national research foundation of Korea (NRF), funded by the Korean Ministry of Science, ICT and Technology (MSIT, project numbers NRF-2017M3A9G6068246 and NRF-2019R1A2C2084652) as well as the Gyeonggi province, Korea. Received: FebruAccepted: Published: May 28, 2021Ĭopyright: © 2021 Delorme et al. PLoS ONE 16(5):Įditor: Manuel Corpas, Universidad Internacional de La Rioja, SPAIN Citation: Delorme V, Woo M, Falcão VCdA, Wood C (2021) PlateEditor: A web-based application for the management of multi-well plate layouts and associated data. ![]()
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